KPV
Also known as Lysine-proline-valine
Alpha-MSH C-terminal tripeptide
The active anti-inflammatory fragment of alpha-MSH, studied for gut and skin inflammation models.
How it works
Enters cells and interferes with NF-kB and inflammatory cytokine transcription without the pigmentation effects of full-length alpha-MSH.
What research has shown
Colitis models report reduced mucosal inflammation and improved barrier integrity; dermatology models report reduced inflammatory lesion scores.
Reported ranges in the literature
Low end
200 mcg daily
Optimal
250 to 500 mcg daily
High end
1 mg daily in research reports
Frequency reported in the literature: Daily
Protocol duration and pairing
Typical study duration
2 to 6 weeks in the gut and skin inflammation models reported.
Research use only
All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.