VIP
Also known as Vasoactive intestinal peptide
28-amino-acid neuropeptide
A signaling peptide studied for pulmonary, immune-modulating and inflammatory-response endpoints.
How it works
Activates VPAC1 and VPAC2 receptors, raising cyclic AMP, relaxing smooth muscle and shifting immune cells toward a regulatory, anti-inflammatory phenotype.
What research has shown
Studies in pulmonary hypertension and inflammatory conditions report reduced inflammatory markers; the native peptide has a very short plasma half-life.
Reported ranges in the literature
Low end
50 mcg daily in reported protocols
Optimal
50 to 150 mcg daily
High end
200 mcg daily
Frequency reported in the literature: Divided daily doses in reported protocols
Protocol duration and pairing
Typical study duration
4 to 12 weeks in the reported inflammatory and pulmonary studies.
Best paired with
Broad anti-inflammatory signaling that overlaps with immune modulator research.
Research use only
All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.