SNAP-8
Also known as Acetyl octapeptide-3
Topical SNARE-competing octapeptide
A topical peptide studied as a mild, non-injected analog of neuromuscular relaxation for expression lines.
How it works
Mimics the N-terminal end of SNAP-25 and competes for a position in the SNARE complex, reducing the efficiency of acetylcholine vesicle docking at the surface level.
What research has shown
Manufacturer and small dermatology studies report reductions in wrinkle depth around 30% over 28 days with twice daily topical use.
Reported ranges in the literature
Low end
Formulations at about 3% in carrier
Optimal
5 to 10% in a topical carrier
High end
10% in reported cosmetic formulations
Frequency reported in the literature: Twice daily topical
Protocol duration and pairing
Typical study duration
8 to 12 weeks of topical use in the cosmetic literature.
Research use only
All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.