Cognitive & Neuro

Semax

ACTH 4-10 heptapeptide analog

A Russian-developed nootropic peptide studied for attention, memory consolidation and stroke recovery.

How it works

Raises BDNF and NGF expression in the hippocampus and modulates dopaminergic and serotonergic tone, without the corticotropic activity of full ACTH.

What research has shown

Russian stroke and cognitive studies report improved recovery scores and attention measures; Western replication is limited.

Reported ranges in the literature

Low end

200 mcg daily intranasal

Optimal

300 to 600 mcg daily

High end

900 mcg daily in reported protocols

Frequency reported in the literature: Daily in 10 to 14 day courses

Protocol duration and pairing

Typical study duration

10 to 30 day courses in the Russian clinical literature.

Best paired with

Semax and Selank together are the standard nootropic pairing, covering BDNF and anxiolytic pathways.

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Research use only

All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.