Oxytocin Acetate
Nonapeptide neurohormone
A hypothalamic nonapeptide studied for social bonding, trust and stress-response endpoints.
How it works
Activates oxytocin receptors in the amygdala, nucleus accumbens and hypothalamus, modulating social salience processing and dampening HPA axis reactivity.
What research has shown
Intranasal trials report changes in trust and social cognition measures, with effect sizes that vary widely across replications.
Reported ranges in the literature
Low end
10 IU intranasal per session
Optimal
24 IU intranasal, the common study dose
High end
40 IU intranasal in dose-ranging studies
Frequency reported in the literature: Per study session
Protocol duration and pairing
Typical study duration
Study windows are short, from single administration to 8 weeks.
Best paired with
Social and pair-bonding endpoints overlap with the sexual function literature.
Research use only
All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.