MGF
Also known as Mechano growth factor, IGF-1Ec
Splice variant of IGF-1
A mechanically induced IGF-1 splice variant studied for satellite cell activation after muscle damage.
How it works
Its unique E domain activates muscle satellite cells and delays their differentiation, expanding the pool of myonuclei available for repair.
What research has shown
Animal studies report increased muscle fiber cross-sectional area after local administration; the native peptide clears within minutes.
Reported ranges in the literature
Low end
100 mcg per site
Optimal
200 mcg per site post-training
High end
400 mcg per session in research reports
Frequency reported in the literature: Post-training on working days
Protocol duration and pairing
Typical study duration
2 to 4 weeks around a training or injury stimulus.
Research use only
All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.