HGH Fragment 176-191
C-terminal growth hormone fragment
The lipolytic tail of the growth hormone molecule, studied for fat metabolism without the growth signaling of full GH.
How it works
Reproduces the lipolytic action of GH on adipocytes through beta-3 adrenergic pathway signaling, without binding the GH receptor or raising IGF-1.
What research has shown
Animal work reports reduced adipose mass; the human clinical program for obesity did not reach its efficacy endpoints.
Reported ranges in the literature
Low end
200 mcg daily
Optimal
250 to 500 mcg daily
High end
500 mcg twice daily in research reports
Frequency reported in the literature: Once or twice daily, typically fasted
Protocol duration and pairing
Typical study duration
12 to 24 week protocols in the lipolysis literature.
Best paired with
Lipolytic fragment without GH receptor activity, so it is grouped with fat metabolism compounds.
Research use only
All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.