Hexarelin Acetate
Ghrelin receptor agonist (hexapeptide)
The most potent GH releasing peptide by weight in comparative studies, with reported cardiac tissue effects.
How it works
Activates GHS-R1a for strong GH release and also binds CD36 in cardiac tissue, which studies link to cardioprotective signaling independent of GH.
What research has shown
Head-to-head work reports the largest GH spike of the GHRP class, with faster receptor desensitization during continuous use.
Reported ranges in the literature
Low end
50 mcg per administration
Optimal
100 mcg, one to two times daily
High end
200 mcg per administration in short blocks
Frequency reported in the literature: One to two times daily in limited blocks. Note: Desensitization is reported faster than with other GHRPs.
Protocol duration and pairing
Typical study duration
4 to 8 weeks; desensitization is reported with longer continuous use.
Best paired with
Most potent GHRP studied, but the shortest useful window before receptor desensitization.
Research use only
All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.