Longevity / Mitochondrial

Epitalon

Also known as Epithalon, AEDG

Pineal tetrapeptide bioregulator

A pineal-derived tetrapeptide studied for telomerase activation and circadian and melatonin rhythm restoration.

How it works

Reported to bind promoter regions that upregulate telomerase reverse transcriptase, and to restore age-related decline in pineal melatonin output.

What research has shown

Cell studies report telomere elongation in somatic cell lines; long-term Russian cohort work reports reduced age-related mortality markers.

Reported ranges in the literature

Low end

5 mg daily for 10 day courses

Optimal

10 mg daily for 10 to 20 day courses

High end

20 mg daily in intensive reported courses

Frequency reported in the literature: Daily in 10 to 20 day courses, one to two times per year

Protocol duration and pairing

Typical study duration

10 to 20 day courses, repeated 2 to 3 times per year in the Russian literature.

Best paired with

Bioregulator protocols are short pulses rather than continuous use, and Epitalon is usually paired with Thymalin.

Build a general wellness protocolView Epitalon at ENOS Labs USA

Research use only

All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.