ACTH 1-39
Also known as Corticotropin
Full-length adrenocorticotropic hormone
The full pituitary corticotropin sequence, used mainly as a diagnostic and reference standard for adrenal function.
How it works
Binds MC2R on the adrenal cortex, driving cortisol and adrenal androgen synthesis through cyclic AMP signaling.
What research has shown
Stimulation testing literature uses it to distinguish primary from secondary adrenal insufficiency by measuring the cortisol response.
Reported ranges in the literature
Low end
1 mcg low-dose stimulation test
Optimal
250 mcg standard stimulation test
High end
Repeat depot protocols in specialist clinical settings only
Frequency reported in the literature: Single administration in test protocols. Note: Primarily a diagnostic reference compound, not a protocol input.
Protocol duration and pairing
Typical study duration
Short diagnostic use, or 2 to 8 weeks in the inflammatory literature.
Best paired with
Studied on its own. No established pairing appears in the literature.
Primarily a diagnostic reference compound rather than a protocol compound.
Research use only
All content on this page is general reference information for laboratory research contexts. It is not medical advice, is not intended to direct human use, and does not replace guidance from a licensed healthcare professional. Not for human consumption. Must be 18+.